Cycloastragenol is a Triterpenoid Saponin Compound Mainly Derived from Plants such as Astragalus Membranaceus

Product Attribute

Cycloastragenol is a Triterpenoid Saponin Compound Mainly Derived from Plants such as Astragalus Membranaceus

Source and extraction method：

Source: Astragalus is a perennial herbaceous plant of the genus Astragalus in the Fabaceae family, 50 - 100 cm tall. The main root is thick, woody, often branched, gray-white. The stem is upright, the upper part is multi-branched, has fine ribs, and is covered with white pubescence. The pinnate compound leaves have 13 - 27 leaflets, 5 - 10 cm long; the petiole is 0.5 - 1 cm long; the stipules are free, ovate, lanceolate or linear-lanceolate, 4 - 10 mm long, and the underside is covered with white soft hair. Leaflets elliptical or oblong-ovate, 7-30 mm long, 3-12 mm wide, apex obtuse or slightly concave, with a small tip or inconspicuous, base rounded, upper surface green, nearly hairless, lower surface covered White soft hair. The racemes are slightly dense, with 10-20 flowers; the total pedicel is almost as long as or longer than the leaves, and is significantly elongated in the fruit stage; the bracts are linear-lanceolate, 2-5 mm long, and the back is covered with white soft Hairy; the pedicel is 3 - 4 mm long, and together with the inflorescence axis is slightly densely covered with brown or black pubescence; the calyx is bell-shaped, 5 - 7 mm long, with white or black pubescence on the outside, sometimes the calyx tube is nearly hairless, with only calyx teeth Hairy, calyx teeth are short, triangular to subulate, only 1/4 - 1/5 of the calyx tube; corolla yellow or light yellow, flag petal obovate, 12 - 20 mm long, slightly concave at the top, short petal at the base Stem, the wing petal is slightly shorter than the flag petal, the petal is oblong, with a short ear at the base, the petiole is about 1 times longer than the petal, the keel petal is nearly the same length as the wing petal, the petal is semi-oval, the petiole is longer than the petal. Slice slightly longer; ovary stalked, finely pubescent. The pod is membranous, slightly swollen, semi-elliptical, 20-30 mm long, 8-12 mm wide, with a prickly tip, white or black pubescence on both sides, and the neck extends beyond the calyx; 3-8 seeds. Its roots are the main part from which cycloastragalus is extracted.

Extraction method:

Organic solvent extraction method: Organic solvents such as ethanol and methanol are commonly used to soak and reflux the roots of Astragalus membranaceus for extraction. For example, astragalus roots are dried and crushed, then soaked in an ethanol solution of a certain concentration, and then heated and refluxed to dissolve cycloastragalinol in the solvent. After operations such as filtration and concentration, an extract containing cycloastragalinol is obtained. It is further purified through column chromatography, recrystallization and other methods to obtain cycloastragalol with higher purity.

Supercritical fluid extraction method: using carbon dioxide in a supercritical state as the extraction agent. Supercritical carbon dioxide has good solvent properties and high diffusivity, can selectively extract cycloastragalin, and can avoid organic solvent residues, which is beneficial to improving the quality of the extract, but the equipment cost is high.

Cycloastragenol is a Triterpenoid Saponin Compound Mainly Derived from Plants such as Astragalus Membranaceus

Product Information

Cycloastragenol is a triterpenoid saponin compound, mainly derived from plants such as Astragalus membranaceus. Its chemical structure is based on cyclopentane pyrophenanthrene and contains multiple functional groups such as hydroxyl groups. This structural feature gives it certain chemical and biological activities.

Physical properties: It is usually a white crystalline powder, odorless and tasteless. In terms of solubility, it has poor solubility in water and has certain solubility in organic solvents such as methanol, ethanol, and chloroform. The melting point is relatively high and the chemical properties are relatively stable, but chemical reactions may also occur under certain conditions (such as strong acid and alkali environments).

Chemical properties: Due to the presence of multiple hydroxyl groups in the molecule, cycloastragenol can undergo esterification reactions to generate corresponding ester compounds. At the same time, it can also undergo complexation reactions with some metal ions, and these reactions have certain applications in research such as pharmaceutical chemistry and chemical modification.

Cycloastragenol is a Triterpenoid Saponin Compound Mainly Derived from Plants such as Astragalus Membranaceus

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